After her PhD, she first focused on the subject of the formation and evolution of the chemical elements in the Universe, studying the Sun, the stars, the Primordial Universe. She then became particularly interested in asteroseismology, the science of the stellar acoustic vibrations, as well as in the extrasolar planetary systems (exoplanets). She wrote about 270 scientific papers in peer-reviewed international journals and she supervised many PhDs. Meanwhile, she gave courses in Physics and Astrophysics in Universities during more than 40 years.
During her career, Sylvie Vauclair had many important national and international responsibilities. President of the French Astronomical and Astrophysical Society, local president of the French Physical Society, member of committees in the European Commission, the Southern European Observatory (ESO), the International Space Science Institute... She is a member of the International Astronomical Union and sits in the Organizing Committee of the commission "Communicating Astronomy with the Public".
Much implied in many different aspects of scientific communication, she is fascinated by the evolution of knowledge over the centuries, in connection with the history of human societies. She wrote a large number of popular books in French (see the "bibliography" page) and frequently gives public talks aimed for a very large public (see the "public talks" page).
She is particularly interested in multidisciplinary actions, discussions and meetings, gathering artists, philosophers, economists, sociologists, psychologists, poets etc. Musics represents an important part of her life. She has a thorough musical formation, which leads her to parallel discussions of music and astronomy in several of her popular books.
She participated in a large number of debates, TV and radio documentaries on many programs. She presently gives a weekly chronicle on a French radio. Her actions and works have received many awards, including ALPHA d'OR de l'ESPACE (1998), le PRIX du CERCLE d'OC (1999), le PRIX du LIVRE SCIENTIFIQUE d’ORSAY (2002), le PRIX de L’ACADEMIE d’OCCITANIE (2007), le GRAND PRIX DES AMIS DE LA CITE DE L’ESPACE (2009), le PRIX DES GOURMETS DE LETTRES (2016).